WHO clinical staging criteria

Stage	Diagnosis
1	Asymptomatic Persistent generalized LAP
2	Unexplained hepatosplenomegaly Extensive wart infection Papular pruritic eruptions Extensive molluscum contagiosum Parotid enlargement Recurrent oral ulcerations Herpes Zoster Lineal gingival erythema Recurrent/ Chronic URTI Fungal nail infections
3	Moderate unexplained malnutrition W/H 70-80% W/A below lower line in growth curve Weight loss > 10% (over 3 months) Failure to gain weight over 6 m in under fives MUAC 11 – 11.9 cm in 1-5 year olds Unexplained persistent diarrhoea (>14days) Unexplained persistent fever (for >1 month) Persistent/ recurrent oral candida Oral hairy leukoplakia Necrotizing gingivitis periodontitis Symptomatic LIP Chronic HIV - lung disease Unexplained anaemia (<8g/dl), neutropenia (<500/mm3) or thrombocytopenia (<50 000/mm3) HIV - cardiomyopathy or nephropathy Lymph node TB Pulmonary tuberculosis Severe recurrent bacterial pneumonia
4	Severe unexplained malnutrition W/H < 70% MUAC < 11 cm in 1-5 year olds Oesophageal candida (or trachea, bronchi, lungs) Central nervous system toxoplasmosis CMV infection (onset at age over 1 month) Pneumocystis pneumonia Acquired HIV-associated rectal fistula Recurrent severe presumed bacterial infections (excluding pneumonia) Progressive multifocal leukoencephalopathy Cerebral or B cell non-Hodgkin lymphoma Herpes simplex infection (for over 1 month) HIV encephalopathy (consult senior) Extrapulmonary tuberculosis Extrapulmonary cryptococcosis Kaposi sarcoma Extrapulmonary TB (excluding LN TB)

Presumed Severe HIV for children under 12 months, who have not had PCR

• Oral candidiasis
• Severe pneumonia
• Severe bacterial sepsis

• PJP
• Oesophageal candidiasis
• Severe wasting
• Toxoplasmosis of the brain
• Cryptococcal Meningits