TB Meningitis
- The most serious complication of TB in childhood, especially in children <2yrs
- Usually, develops 6-12 months after initial TB infection
Clinical signs and symptoms
Insidious onset - behaviour change, headache, FTT
May present with cranial nerve palsy, coma, hemiplegia, convulsions
Investigations
- CSF - may be confused with bacterial meningitis
- Low CSF glucose, raised protein, may initially have low cell count with polymorph
predominance
- Repeat CSF if no response to Antibiotics - increased protein and cell count
- CT/MRI brain - basal enhancement with contrast, +/- hydrocephalus
Treatment
see TB treatment