| DRUG | ROUTE | EACH DOSE | TIMES DAILY | NOTES/ INDICATIONS |
|---|---|---|---|---|
| Ampicillin | IV/IM | 25 mg/kg 50 mg/kg |
< 7 days: BD if < 2 kg TDS if > 2kg > 7 days: BD if < 1.2 kg TDS if 1.2-2 kg QID if > 2 kg |
Sepsis, Meningitis |
| Adrenaline | IV | 0.1ml/kg of 1:10000 | STAT | CPR |
| Aminophylline | PO | Loading dose: 6 mg/kg Maintenance dose: 2.5 mg/kg |
STAT BD |
Respiratory stimulants
(Apnoea) Preparation and dosing |
| Benzylpenicillin | IV | 50000 IU/kg in Sepsis, Pneumonia, Syphilis etc. 100000 IU/kg in Meningitis |
BD if <7 days QID if > 7 days |
Sepsis, Syphilis, Meningitis |
| Ceftriaxone | IV | Meningitis or Severe Infection: 100 mg/kg Other infections 50 mg/kg |
OD | Sepsis,
Meningitis Bloody diarrhoea: 5 days |
| Chlorhexidine (CHX) | locally | to the tip of the cord, the stump and around the base of the stump | STAT | Apply CHX. once within 24 hours after the birth, but preferably in the first 2 hrs |
| Ciprofloxacin | PO | 7.5mg/kg | OD | Bloody diarrhoea: 3 days |
| Cotrimoxazole | PO | CPT: Cotrimoxazole preventative therapy: 120 mg OD (dispersible paediatric tablet or ¼ adult tablet) High dose in PJP: 120mg/kg/day given 8 hourly for 3 weeks, maximum dose 1920mg/day |
OD | CPT |
| Diazepam | PR | 0.1mg/kg Volume: 0.3 ml of 10 mg/2 ml solution (<4 kg) |
STAT | Convulsion. CAVE resp. depression Only give if beyond 2 weeks |
| (Flu)cloxacillin | IV/IM | 50 mg/kg |
BD if < 7 days QID if > 7 days |
Skin infections. |
| Gentamicin | IV/IM | LBW < 7 days: 3 mg/kg Term < 7 days: 5 mg/kg > 7 days 7.5 mg/kg |
OD | Sepsis,
Meningitis Oto- and nephrotoxicity |
| Iron supplements | PO | 2–4 mg/kg Syrup usually contains 50mg iron in 5 mls or 10mg per ml |
OD | Preterm neonates from 2 weeks if tolerating full enteral feeds until 6 months of age |
| Isoniazid | PO | Dose accuratly if syrup is available: 10 mg/kg/day If only tablets are available: < 2500g: 25mg (1/4 tablet) every 24 hours 2500-5000g: 50mg (1/2 tablet) every 24 hours |
OD | Exposure to TB |
| Metronidazole | IV | 7.5 mg/kg | TDS | Intra-abdominal infections (e.g. NEC) |
| Multivitamin preparation | PO | 0.3-0.6ml (5-10 drops)/ day = vitamin A of 1000 IU/day and vitamin D 400 iu/day) |
OD | Preterm neonates if tolerating full enteral feeds until 6 months of age |
| Nevirapine | oral | <2500g: 1 ml syrup >2500g: 1.5 ml syrup |
OD | For six weeks in HIV exposed neonates |
| Paraldehyde | IM | 0.2mls/kg (2kg: 0.4mls, 3kg: 0.6mls, 4kg: 0.8mls) |
STAT can be repeated 1 x after 10 min |
Convulsion Do not leave in plastic syringe for longer than 10-15 min. Should not be given IV. Preferable to give rectally |
| PR | 0.4mls/kg (2kg: 0.8mls, 3kg: 1.2mls, 4kg: 1.6mls) |
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| Phenobarbitone | IM | Loading dose: 20 mg/kg Volume: if < 2kg: 0.2 mls if > 2 kg: 0.3 mls | STAT can be repeated 1x after 10 min |
Convulsion * Volumes assumes that the Phenobarbitone being used is of 200mg/ml preparation. |
| PO | Maintenance dose: 2.5-5 mg/kg | nocte | ||
| Prednisolone | PO | in PJP: 2mg/kg | OD | for 7 days, than wean off over 2 weeks (1mg/kg/day for 7 days, 0.5mg/kg/day for a further 7 days |
| Tetracycline Eye Ointment (TEO) | local | both eyes once after birth | STAT | at birth |
| Vitamin K | IM | preterm: 0.5 mg term: 1 mg |
STAT | at birth, Routine care, >Preterms/LBW |
| slowly IV | Neonatal Vit K deficiency bleeding 1 mg | STAT to TDS | ||
| Zinc | PO | 1/2 tablet (10 mg) per day for 10 days | OD | Diarrhoea |